NeuroscienceeLifePeer-reviewed
Myelin dystrophy in the aging prefrontal cortex leads to impaired signal transmission and working memory decline: a multiscale computational study
Sara Ibañez, Nilapratim Sengupta, Jennifer Irene Luebke…·Christina M. Weaver
This study uses computational models to show that age-related myelin dystrophy in the prefrontal cortex impairs working memory by reducing conduction velocity and increasing action potential failures.
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