Yutaka Takaoka

This study predicts that the SARS-CoV-2 XBB.1.5 variant may spread more widely and faster than other variants based on molecular docking and evolutionary analysis.

The paper predicts SARS-CoV-2 infectivity using a mathematical model combining molecular docking simulations and phylogenetic analysis of spike protein variants.

The paper predicts that the SARS-CoV-2 BA.2.75 variant has higher infectivity than previous variants due to increased spike protein evolutionary distance and docking affinity with ACE2.

The paper establishes an IGHD2 mouse model to study GH deficiency, finding reduced Ghrhr and Gh promoter activities due to decreased nuclear CREB3L2 levels, revealing a novel molecular mechanism.