Author

Kaifu Gao

Michigan State UniversityORCID 0000-0001-7574-4870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:machine learning (classical)· 2 Assay:protein structure· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Duc Duy NguyeniD· 2 shared Guo‐Wei WeiiD· 2 shared Rui WangiD· 2 shared Jiahui CheniD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Duc Duy NguyenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 5, 2020

Potentially highly potent drugs for 2019-nCoV

Duc Duy Nguyen, Kaifu Gao, Jiahui Chen…·Guo‐Wei Wei

Structure-based drug repositioning using a homology model of the 2019-nCoV 3CL protease screens 1465 FDA-approved DrugBank compounds to identify candidate therapeutics against the virus.

58 citations

statistical modelmachine learning (classical)

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJan 30, 2020

Machine intelligence design of 2019-nCoV drugs

Kaifu Gao, Duc Duy Nguyen, Rui Wang, Guo‐Wei Wei

The 2019-nCoV protease shares 96.1% sequence identity and near-identical inhibitor binding sites with SARS-CoV, so a generative machine-learning model proposes candidate inhibitors; existing HIV drugs are also assessed.

53 citations

virusprotein structure

𝕏 PostBluesky