Jiahui Chen

This paper introduces DRAM, a method for transcriptome-wide m5C detection using deaminase and reader proteins, showing high overlap with BS-seq data and supporting low-input RNA.

Structure-based drug repositioning using a homology model of the 2019-nCoV 3CL protease screens 1465 FDA-approved DrugBank compounds to identify candidate therapeutics against the virus.

The paper identifies cancer-associated T cells using TCR repertoire and gene expression data, revealing novel regulators and antigens with potential for immune monitoring and immunotherapy.