Author

Sandra Vidak

National Institutes of HealthORCID 0000-0001-7579-8545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1

Frequent Co-Authors

Tom MisteliiD· 2 shared Amit K. BeheraiD· 1 shared Arun Prasath DamodaraniD· 1 shared Bandana KumariiD· 1 shared Ethan Dickson· 1 shared Eugene ValkoviD· 1 shared Filip PekoviciD· 1 shared Gerard Duncan· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Tom MisteliORCID

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2 papers

Recent·Most cited

Cell BiologyNucleusPeer-reviewedJan 5, 2026

Transcriptional profiling of Hutchinson-Gilford Progeria patients identifies primary target pathways of progerin

Sandra Vidak, Sohyoung Kim, Tom Misteli

This study identifies primary target pathways of progerin in HGPS patients through transcriptomic analysis, revealing mTORC1, UPR, UV response, apoptosis, and TNF signaling as key affected pathways.

4 citationstop 3%

humanbulk RNA-seq

GeneticsMolecular CellPeer-reviewedDec 30, 2025

RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria

Amit K. Behera, Jeongjin J. Kim, Shreya Kordale…·Thomas Gonatopoulos-Pournatzis

The paper introduces CRASP-Seq, a method to identify gene regulators of alternative splicing, and finds ZNF207 regulates LMNA splicing in progeria by interacting with U1 snRNP.

6 citations

humanCRISPR screen