Thomas Gonatopoulos-Pournatzis

The paper identifies U2AF2's role in intron retention of lncRNAs PURPL and MALAT1, showing how this process affects their localization and promotes cell proliferation and migration.

The paper introduces CRASP-Seq, a method to identify gene regulators of alternative splicing, and finds ZNF207 regulates LMNA splicing in progeria by interacting with U1 snRNP.

This study identifies Aurora-A as a splicing kinase that regulates alternative splicing by phosphorylating splicing factors and altering RNA motifs in affected regions.