Author

Zijie Zheng

Fudan UniversityORCID 0000-0001-7622-0470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Dongliang LiuiD· 2 shared Huaizong SheniD· 2 shared Yannan Qu· 2 shared Deng PaniD· 1 shared Fan Li· 1 shared Haopeng YuiD· 1 shared Jiacheng MaiD· 1 shared Jiexin Chen· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Dongliang LiuORCID

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2 papers

Recent·Most cited

BiochemistryPlant CommunicationsPeer-reviewedFeb 19, 2025

AtKC1 inhibits AtAKT1 activation via its amino-terminal inhibitory domain

Zijie Zheng, Yannan Qu, Jiexin Chen…·Huaizong Shen

The paper identifies an inhibitory domain in AtKC1 that stabilizes the closed conformation of AKT1, preventing its activation, and shows a stoichiometry change in a mutant form.

3 citations

plant (other)structural biology

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Molecular BiologybioRxivPreprintJul 3, 2023

Structure and engineering of miniature Acidibacillus sulfuroxidans Cas12f1

Zhaowei Wu, Dongliang Liu, Deng Pan…·Quanjiang Ji

The paper reports the structure of AsCas12f1 and engineers it to enhance genome editing activity in human cells.

DOI 10.1101/2023.07.03.547593

humanCRISPR screen

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