Jeffrey M. Purkerson

The paper introduces RomicsProcessor, a reproducible-by-design tool for multi-omics and spatial-omics analysis that enforces FAIR principles and ensures computational reproducibility.

FUSION is a web-based tool that integrates spatial -omics data with histology to analyze tissue states and identify spatial linkages between molecular and histopathologic features.

The paper analyzes endothelial cell environments across organs using spatially resolved omics data and provides an interactive tool for visualizing cell distances and neighborhoods.

This study uses sorted-cell proteomics to identify BPD-specific proteome changes in epithelial and endothelial cells, revealing cornification-associated proteins and redox imbalance.

This paper constructs a 3D map of neurovascular nephron connectivity in the human kidney across the lifespan and identifies structural changes in development and disease.

The paper creates a high-resolution multimodal lung atlas using single-nucleus RNA and chromatin data from 11 healthy adults, identifying 70 cell populations and 332,846 chromatin regions.

The paper integrates N-glycan analysis with CODEX imaging to identify cell-specific glycosylation patterns in healthy human lung tissue.

This paper describes the construction and usage of the Human Reference Atlas (HRA) v2.0, which integrates multiscale data across 36 organs and provides tools for analysis and visualization.