Anil Chougule

This study identifies NM2A motor activity as a key component of bipolar filament depolymerization, working with tail-dependent mechanisms to enable NM2A turnover and NM2B reorganization in cells.

This study shows that NM2A's tail, phosphorylation sites, and motor domain synergistically enhance NM2B filament turnover and cell motility, while phosphomimetic NM2B tails only locally affect NM2B unless combined with NM2A.