Codon-optimized TDP-43-mediated neurodegeneration in a Drosophila model for ALS/FTLD
Tanzeen Yusuff, Shreyasi Chatterjee, Ya‐Chu Chang, Tzu‐Kang Sang, George R. Jackson
This study creates a Drosophila model expressing codon-optimized human TDP-43, showing neurodegenerative phenotypes and toxic protein aggregation.
bioRxiv · Jul 10, 2019 · PreprintNeuroscience