Julien Yann Dutheil

This paper introduces a maximum-likelihood framework to estimate gene expression noise from scRNA-seq data, accounting for technical noise and cell type heterogeneity, and demonstrates its reproducibility using yeast data.

This study identifies two sRNAs in Staphylococcus aureus that regulate zinc homeostasis, showing their role in Zn-sparing responses and adaptation to metal limitation.

This study maps lineage-specific rate shifts in protein sequences across the tree of life, finding they are widespread and influenced by evolutionary ancestry and phylogenetic depth.

The paper investigates selection signals and coevolution among imprinted genes in Arabidopsis lyrata using phylogenetic and population genomic approaches, finding balancing selection and coevolution but limited directional selection.

PolarBEAR polarizes SNPs and estimates uSFS without outgroup data, showing high accuracy in simulations and human data, with robustness to mutation models.

The paper tests the fitness effect of a de novo evolved mouse gene by comparing knockout and wildtype strains in a reproductive competition experiment.

This paper analyzes the population genomics of Ustilago maydis, finding two subpopulations with a recent bottleneck and higher adaptive mutation rates in virulence cluster genes.