Author

Jason Laird

Johns Hopkins UniversityORCID 0000-0001-7769-5697Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aditya DendukuriiD· 1 shared Aidan L. Morson· 1 shared Alex SpaethiD· 1 shared Alexandra MaertensiD· 1 shared Andreas R. HierlemanniD· 1 shared Archana NagarajaniD· 1 shared Bradley M. ColquittiD· 1 shared Christine W. LaryiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperNeuroscience

Aditya DendukuriORCID

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3 papers

Recent·Most cited

NeuroscienceNature NeurosciencePeer-reviewedNov 24, 2025

Protosequences in brain organoids model intrinsic brain states

Tjitse van der Molen, Alex Spaeth, Mattia Chini…·Tal Sharf

This study shows that structured firing sequences emerge in human and murine brain organoids and neonatal brain slices, suggesting innate rather than experience-dependent neural coding.

22 citationstop 1%

humanmouse

NeurosciencebioRxivPreprintOct 26, 2023

Transcriptomic network analysis of brain and bone reveals shared molecular mechanisms underlyingAlzheimer's Disease and related dementias and Osteoporosis

Archana Nagarajan, Jason Laird, Obiadada Ugochukwu…·Christine W. Lary

The paper identifies shared molecular mechanisms between Alzheimer's Disease and Osteoporosis using transcriptomic network analysis across brain and bone tissues.

DOI 10.1101/2023.10.26.559969

humanbulk RNA-seq

BioinformaticsbioRxivPreprintJan 25, 2021

Personalized Perturbation Profiles Reveal Concordance between Autism Blood Transcriptome Datasets

Jason Laird, Alexandra Maertens

The paper identifies 1,189 commonly perturbed genes in ASD blood transcriptomes using personalized perturbation profiles and links them to cellular processes like DNA damage and autophagy.

2 citations

humanbulk RNA-seq