Author

Alexandra Maertens

Johns Hopkins UniversityORCID 0000-0002-2077-2011Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Alexandra Maertens1 paper

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Aakriti MathuriD· 1 shared Alex Rittenhouse· 1 shared André KleensangiD· 1 shared Chloe M. KashiwagiiD· 1 shared Emily J. IllingworthiD· 1 shared Fenna C.M. SilléiD· 1 shared Jason LairdiD· 1 shared Jason LairdiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aakriti MathurORCID

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3 papers

Recent·Most cited

Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta

Kristal A. Rychlik, Sylvia S. Sanchez, Chloe M. Kashiwagi, Jin-Shiung Liao, Aakriti Mathur, Emily J. Illingworth, André Kleensang, Alexandra Maertens, Fenna C.M. Sillé

This study examines gene expression changes in fetal liver, heart, lung, and placenta after prenatal arsenic exposure in mice, identifying immune-related pathway alterations and reduced Gbp3 expression in female placentas.

Toxicology · Feb 10, 2026Peer-reviewedPharmacology & Toxicology

Genetic Background and Sex Modulate Androgen Responses in Human Brain Microphysiological System

Maren Schenke, Jason Laird, Alex Rittenhouse, Viktoriya Kucheryavenko, Winfried Neuhaus, Ou Chen, Sarven Sabunciyan, Alexandra Maertens, Lena Smirnova

This study shows that androgen responses in human brain organoids vary by genetic background and sex, affecting transcription, cell populations, and DNA methylation.

bioRxiv · Dec 8, 2025 · PreprintNeuroscience

Personalized Perturbation Profiles Reveal Concordance between Autism Blood Transcriptome Datasets

Jason Laird, Alexandra Maertens

The paper identifies 1,189 commonly perturbed genes in ASD blood transcriptomes using personalized perturbation profiles and links them to cellular processes like DNA damage and autophagy.

bioRxiv · Jan 25, 2021 · PreprintBioinformatics