ImmunologyBiomedicine & PharmacotherapyPeer-reviewed
A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease
Michele Biagioli, Cristina Di Giorgio, Carmen Massa…·Stefano Fiorucci
This study identifies 3-oxo-DCA as a microbial bile acid that acts as a GPBAR1 agonist and RORγt inverse agonist, reversing inflammation in IBD.
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