Role of oligodendroglial ADAM10 in oligodendrocyte maturation, myelination and myelin maintenance
Mathis Lavaud, Aïda Padilla-Ferrer, Anne Simon, Pilar Acebo, Céline Dargenet-Becker, Victor Gorgievski, Eleni T. Tzavara, Charbel Massaad, Mehrnaz Jafarian-Tehrani, Delphine Meffre
This study investigates the role of oligodendroglial ADAM10 in myelin development and maintenance, finding that its deficiency causes delayed oligodendrocyte maturation and myelin defects with sexual dimorphism in adult mice.
bioRxiv · Jul 25, 2025 · PreprintNeuroscience