Venkat Krishnan Sundaram

Across three German sites and 207 analyzed mice, systemic rhNRGβ1 at 10 µg/kg did not reduce schwannoma nerve thickness or shift Schwann cell differentiation markers.

This study shows that using a robust statistical method to select reference genes from randomly chosen candidates is as effective as selecting stable genes from RNA-Seq data for qPCR normalization.

This study identifies the timing of Schwann cell developmental transitions in dissociated DRG/Schwann cell cocultures by comparing gene expression profiles to developing spinal nerves.

The paper evaluates four statistical methods for validating reference gene stability in longitudinal studies and proposes a combined workflow for improved accuracy.