Kirill V. Tarasov

This study identifies transcriptomic changes in the sinoatrial node of mice overexpressing AC8, revealing altered pathways and transcription factors linked to cardiac aging and disease.

The paper integrates phosphoproteomics, proteomics, and transcriptomics to show that reprogramming of cardiac signaling pathways enhances resilience to chronic adenylyl cyclase stress.

The paper compares age-related molecular changes in left ventricle and sinoatrial node cells from young and old C57 mice using transcriptomic analysis to identify age-associated gene expression patterns and regulatory mechanisms.

This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.

This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.