NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Comprehensive preclinical evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease
Mélanie Jambeau, Kevin D. Meyer, Marián Hruška-Plocháň…·Clotilde Lagier‐Tourenne
This study evaluates human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease, showing mixed effects on poly-GA levels and disease progression.