Author

Zhen Zhang

Shandong Provincial HospitalORCID 0000-0001-7825-2679Unclaimed ORCID profile · follow to get notified of new preprints

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Zhen Zhang6 papers · Baylor College of Medicine

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Fan LiuiD· 1 shared Ping XieiD· 1 shared Shiyao Sun· 1 shared Sihui Ling· 1 shared Weixiao Liu· 1 shared Xiaokun Jiang· 1 shared Yawen Tan· 1 shared Yaxin Shang· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Fan LiuORCID

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedJun 18, 2025

PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

Fan Liu, Weixiao Liu, Yawen Tan…·Ping Xie

This study shows that PTEN neddylation promotes resistance to CDK4/6 inhibitors in breast cancer by activating the PI3K/Akt pathway and AP-1 transcription factor, and identifies Echinacoside as a potential inhibitor.

5 citations

humanexperimental assay

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