Author

Leanna S. Morinishi

University of California, San FranciscoORCID 0000-0001-7869-4012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander M. WolffiD· 1 shared Alison M. MaxwelliD· 1 shared Andrew M. NataleiD· 1 shared Beatrice E. AryiD· 1 shared Bruk MensaiD· 1 shared Charlotte NelsoniD· 1 shared Cole V. M. HelselliD· 1 shared Cynthia M. ChioiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Alexander M. WolffORCID

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2 papers

Recent·Most cited

Systems BiologyCell SystemsPeer-reviewedJul 1, 2020

Loss of Tet2 affects proliferation and drug sensitivity through altered dynamics of cell-state transitions

Leanna S. Morinishi, Karl Kochanowski, Ross L. Levine…·Steven J. Altschuler

This study shows that Tet2 loss-of-function in AML cells alters cell-state transitions, improving survival during drug treatment and contributing to relapse.

32 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsBiology OpenPeer-reviewedJul 15, 2018

Extending Chemical Perturbations Of The Ubiquitin Fitness Landscape In A Classroom Setting

David Mavor, Kyle A. Barlow, Daniel E. Asarnow…·James S. Fraser

The paper uses deep mutational scanning to explore how chemical perturbations affect ubiquitin's mutational tolerance, revealing sensitization of most positions except two.

25 citations

proteomicsdeep learning

𝕏 PostBluesky