Author

Alison M. Maxwell

University of California, San FranciscoORCID 0000-0002-6129-7683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Daniel M. C. SchwarziD· 2 shared Douglas R. WassarmaniD· 2 shared Taylor ArhariD· 2 shared Adam Catching· 1 shared Aji Palar· 1 shared Alexander M. WolffiD· 1 shared Andrew F. Kung· 1 shared Andrew M. NataleiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Daniel M. C. SchwarzORCID

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2 papers

Recent·Most cited

Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding

Robert W. Newberry, Taylor Arhar, Jean Costello, George C. Hartoularos, Alison M. Maxwell, Zun Zar Chi Naing, Maureen Pittman, Nishith R. Reddy, Daniel M. C. Schwarz, Douglas R. Wassarman, Taia S. Wu, Daniel Barrero, Christa Caggiano, Adam Catching, Taylor B. Cavazos, , Jenna Pell

The paper uses deep mutational scanning in yeast to show that a toxic conformation of α-synuclein is stable under chemical perturbations, while mutations affecting toxicity are influenced by these perturbations.

bioRxiv · May 1, 2020Biochemistry

Extending Chemical Perturbations Of The Ubiquitin Fitness Landscape In A Classroom Setting

David Mavor, Kyle A. Barlow, Daniel E. Asarnow, Yuliya Birman, Derek Britain, Weilin Chen, Evan M. Green, Lillian R. Kenner, Bruk Mensa, Leanna S. Morinishi, Charlotte Nelson, Erin M. Poss, Pooja Suresh, Ruilin Tian, Taylor Arhar, , James S. Fraser

The paper uses deep mutational scanning to explore how chemical perturbations affect ubiquitin's mutational tolerance, revealing sensitization of most positions except two.

Biology Open · Jul 15, 2018Peer-reviewedBioinformatics