SARS-CoV-2 5'-UTR stem-loops activate the antiviral protein oligoadenylate synthetase 1 (OAS1)
Alejandro Oviedo, Camden R. Bair, Alexander P. Vasilakopoulos, Kierra Regis, David VanInsberghe, Anice C. Lowen, Graeme L. Conn
This study identifies a conserved SARS-CoV-2 5-UTR stem-loop region that activates OAS1, a key antiviral protein, through structural and functional analyses.
Journal of Biological Chemistry · May 25, 2026Peer-reviewedBiochemistry