Author

Ravi Ojha

University of HelsinkiORCID 0000-0001-7876-4607Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ravi Ojha1 paper · University of Helsinki;

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Giuseppe BalistreriiD· 2 shared Pinja KettuneniD· 2 shared Taisia RõlovaiD· 2 shared Angelina LesnikovaiD· 1 shared Anja KipariD· 1 shared Bahaa Al-mhanawiiD· 1 shared Ernst Jurgen WolvetangiD· 1 shared Janika RuuskaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Giuseppe BalistreriORCID

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2 papers

Recent·Most cited

MicrobiologyMolecular Therapy — Nucleic AcidsPeer-reviewedOct 1, 2025

SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes accumulation of HIF1alpha and phosphorylated tau

Pinja Kettunen, Janika Ruuska, Tania Quirin…·Giuseppe Balistreri

This study shows SARS-CoV-2 infects hiPSC-derived neurons via endosomal-lysosomal pathway dependent on cathepsins, leading to HIF1alpha accumulation and phosphorylated tau, suggesting neurodegenerative effects.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 14, 2022

SARS-CoV-2 infection of human neurons requires endosomal cell entry and can be blocked by inhibitors of host phosphoinositol-5 kinase

Pinja Kettunen, Angelina Lesnikova, Noora Räsänen…·Giuseppe Balistreri

This study shows that SARS-CoV-2 can infect a small fraction of human cortical neurons via the endosomal pathway, and this infection can be blocked by apilimod.

2 citations

humanexperimental assay

𝕏 PostBluesky