Author

Benjamin L. George

National University of SingaporeORCID 0000-0001-7887-2333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anissa Anindya WidjajaiD· 3 shared Eleonora AdamiiD· 3 shared Jessie Tan· 3 shared Sebastian SchäferiD· 3 shared Sivakumar ViswanathaniD· 3 shared Stuart A. CookiD· 3 shared Brijesh Kumar SinghiD· 2 shared Chee Jian PuaiD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Anissa Anindya WidjajaORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 9, 2023

Inhibition of an immunometabolic axis of mTORC1 activation extends mammalian healthspan

Anissa Anindya Widjaja, Wei‐Wen Lim, Sivakumar Viswanathan…·Stuart A. Cook

This study shows that inhibiting IL11 improves healthspan in aged mice by reversing metabolic dysfunction, sarcopenia, and frailty.

3 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintJun 10, 2021

Molecular dissection of pro-fibrotic signaling identifies the mechanism underlying IL11-driven fibrosis gene translation, reveals non-specific effects of STAT3 and suggests a new mechanism of action for nintedanib

Anissa Anindya Widjaja, Sivakumar Viswanathan, Dong Jinrui…·Stuart A. Cook

The paper investigates IL11-driven fibrosis mechanisms, showing ERK, not STAT3, drives fibrogenesis and identifies a novel role for nintedanib in inhibiting pro-fibrotic translation.

DOI 10.1101/2021.06.10.447846

mouseproteomics

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GenomicsCirculationPeer-reviewedJul 9, 2019

Translational control of cardiac fibrosis

Sonia Pankaj Chothani, Sebastian Schäfer, Eleonora Adami…·Owen J. L. Rackham

The paper identifies translational regulators of fibrogenic genes in human cardiac fibroblasts and shows their role in cardiac fibrosis through ribosome profiling and RNA-binding protein analysis.

122 citationstop 1%

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