Author

Simone Iwabe

Charles River Laboratories (United States)ORCID 0000-0001-7889-0013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Ripolles‐GarciaiD· 2 shared Gustavo David AguirreiD· 2 shared Valérie DufouriD· 2 shared William A. BeltraniD· 2 shared Alexa P. GrayiD· 1 shared Artur V. CideciyaniD· 1 shared Evelyn SantanaiD· 1 shared John G. FlanneryiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Ana Ripolles‐GarciaORCID

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedMar 22, 2022

Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness

Keiko Miyadera, Evelyn Santana, Karolina P. Roszak…·Gustavo David Aguirre

This paper demonstrates that AAV gene therapy targeting ON-bipolar cells in a canine model of LRIT3-CSNB significantly improves night vision and restores LRIT3 function.

30 citations

experimental assay

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NeuroscienceMolecular TherapyPeer-reviewedMar 27, 2021

Gene Therapy Reforms Photoreceptor Structure and Restores Vision in NPHP5-associated Leber Congenital Amaurosis

Gustavo David Aguirre, Artur V. Cideciyan, Valérie Dufour…·William A. Beltran

This paper demonstrates that gene therapy using AAV-mediated NPHP5 augmentation restores photoreceptor structure and function in a canine model of Leber congenital amaurosis.

31 citations

mousehuman

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