Gustavo David Aguirre

The paper uses fMRI to assess cone-driven responses in canine retinal disease models, finding preserved responses in some models and restored function in NPHP5-CRD2 after gene augmentation.

This paper demonstrates that AAV gene therapy targeting ON-bipolar cells in a canine model of LRIT3-CSNB significantly improves night vision and restores LRIT3 function.

This paper demonstrates that gene therapy using AAV-mediated NPHP5 augmentation restores photoreceptor structure and function in a canine model of Leber congenital amaurosis.