NeurosciencebioRxivPreprint
Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model
Junxiang Yin, Jennifer White, Swati Khare…·Michael F. Waters
This study creates a novel SCA13 mouse model with a R424H mutation, showing motor deficits, Purkinje cell loss, cerebellar inflammation, and atrophy, linking neuroinflammation to neurodegeneration.