Junxiang Yin

Intra-arterial Deoxyribonuclease therapy improves stroke outcomes in aged mice

This study shows that intra-arterial DNase therapy improves stroke outcomes in aged mice by enhancing reperfusion and reducing NETs.

Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model

This study creates a novel SCA13 mouse model with a R424H mutation, showing motor deficits, Purkinje cell loss, cerebellar inflammation, and atrophy, linking neuroinflammation to neurodegeneration.

A Novel Early Onset Spinocerebellar Ataxia 13 BAC Mouse Model with Cerebellar Hypoplasia, Tremor, and Ataxic Gait

This paper presents a novel BAC mouse model of SCA13 with cerebellar hypoplasia, tremor, and ataxic gait, mimicking human disease features.