Author

Hanwen Zhou

Jiangnan UniversityORCID 0000-0001-7894-7948Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Di Zhang· 1 shared Hengwei ZhangiD· 1 shared Hongxuan Wu· 1 shared Jiajia YouiD· 1 shared Weiguo Zhang· 1 shared Xian ZhangiD· 1 shared Xuewei PaniD· 1 shared Zan ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Di Zhang

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1 paper

Recent·Most cited

The two-component nuclease-active KELShedu system confers broad antiphage activity via abortive infection

Hengwei Zhang, Jiajia You, Hanwen Zhou, Zan Zhang, Hongxuan Wu, Di Zhang, Xuewei Pan, Weiguo Zhang, Xian Zhang, Zhiming Rao

The paper characterizes the KELShedu system in E. coli, showing it confers antiphage activity through abortive infection by degrading DNA when NTP levels drop during phage invasion.

Science Advances · Oct 31, 2025Peer-reviewedMicrobiology