Alex Dranovsky

This study shows that adult-born neurons maintain hippocampal cholinergic inputs and support working memory during aging by sustaining septohippocampal circuits.

The paper inhibits norepinephrine signaling during a sensitive period in mice, revealing long-term effects on emotional behaviors and LC-NE circuitry in adulthood.

This study shows that ablating proliferating neural stem cells during early life reduces adult hippocampal neurogenesis, even when the stem cell pool is not significantly depleted.

This study demonstrates that iPSC-derived neurons express antipsychotic drug targets and respond to ligands, showing clozapine modulates glutamatergic and serotonergic responses in distinct neuronal populations.