Author

Mynor J. Mendez Valdez

University of MiamiORCID 0000-0001-7899-0751Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam M. SonabendiD· 1 shared Alexandra Alvarado Medina· 1 shared Anna Jane Hudson· 1 shared Antonio IavaroneiD· 1 shared Ashish Harish ShahiD· 1 shared Ava AmideiiD· 1 shared Avindra NathiD· 1 shared Catherine DeMarinoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam M. SonabendORCID

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1 paper

Recent·Most cited

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma

Deepa Seetharam, Jay S. Chandar, Christian Kieran Ramsoomair, Jelisah Desgraves, Alexandra Alvarado Medina, Anna Jane Hudson, Ava Amidei, Jesús Castro, Vaidya Govindarajan, Sarah Wang, Yong Zhang, Adam M. Sonabend, Mynor J. Mendez Valdez, Dragan Maric, Vasundara Govindarajan, , Ashish Harish Shah

This study shows targeting ZNF638 induces viral mimicry and enhances immune checkpoint inhibition in glioblastoma by increasing dsRNA signaling and PD-L1 expression.

Journal of Clinical Investigation · Mar 16, 2025Peer-reviewedCancer Biology