Author

Deepa Seetharam

University of MiamiORCID 0000-0002-4886-5025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Christian Kieran RamsoomairiD· 2 shared Defne BayıkiD· 2 shared Michele CeccarelliiD· 2 shared Adam M. SonabendiD· 1 shared Alexandra Alvarado Medina· 1 shared Anna Hudson· 1 shared Anna Jane Hudson· 1 shared Antonio IavaroneiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Christian Kieran RamsoomairORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 12, 2026

Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas

Christian Kieran Ramsoomair, Victoria Álvarez, Felipe Sarmiento…·Ashish H Shah

This study identifies ADAR as a key mediator of immune evasion in H3K27M+ pediatric gliomas and shows that ATRA can induce ADAR degradation, enhancing antiviral responses and tumor immunogenicity.

DOI 10.64898/2026.05.08.723800

humanbulk RNA-seq

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Cancer BiologyJournal of Clinical InvestigationPeer-reviewedMar 16, 2025

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma

Deepa Seetharam, Jay S. Chandar, Christian Kieran Ramsoomair…·Ashish Harish Shah

This study shows targeting ZNF638 induces viral mimicry and enhances immune checkpoint inhibition in glioblastoma by increasing dsRNA signaling and PD-L1 expression.

19 citationstop 2%

mousehuman

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