Dragan Maric

This study identifies GPR183 as a driver of peripheral sensitization in rodents and humans, showing its role in pain pathways through immune cell activation and highlighting its potential as a therapeutic target.

This study identifies phosphoproteomic dysregulation as a driver of tumor proliferation in Cushing's disease and demonstrates reversibility using an FDA-approved PP2A agonist.

This study characterizes a new pluripotent state in RSeT hESCs, showing resistance to naive and formative conversion and distinct transcriptomic and signaling features.

This study shows targeting ZNF638 induces viral mimicry and enhances immune checkpoint inhibition in glioblastoma by increasing dsRNA signaling and PD-L1 expression.

This study transplants rat cortical progenitors into adult rat brains to create brain-like tissues and assesses their integration and connectivity across different host ages.

This study identifies a unique metabolic state in RSeT human embryonic stem cells characterized by quadrivalency, linking it to growth independence from oxygen and resistance to naive reprogramming.

This paper presents a cellular taxonomy of the adult human spinal cord using single nucleus RNA-sequencing and spatial transcriptomics, identifying 29 glial and 35 neuronal clusters and highlighting motoneuron vulnerability to ALS.

This study uses MRI to detect early cerebrovascular pathology and track antiviral T cells in a murine model of CNS infection.

This study uses single-cell RNA sequencing to reveal transcriptional heterogeneity in ventricular zone cells of the embryonic mouse forebrain, showing spatial and temporal gene expression differences.

This study identifies Grin1 as a key regulator of subtype-specific gene expression in MGE-derived interneurons, linking NMDAR signaling to neurodevelopmental disorders like schizophrenia.

The paper profiles single nucleus RNA-seq data from spinal cord tissue after injury to identify repair-related cellular mechanisms and potential therapeutic targets.