Ana Julia Velez Rueda

This paper identifies a novel Ca2+-binding motif in MICU1 that functions as an early sensor, triggering structural changes that refine its regulatory role in mitochondrial Ca2+ uptake.

CaviDB is a database of protein cavities and their features, integrating structural and functional data to support drug design and protein function studies.

This study evaluates AlphaFold2's ability to predict ensemble protein conformations and finds it struggles with conformational diversity, with performance worsening as diversity increases.

The paper identifies a conserved promiscuous reaction in serum albumins across mammals and suggests evolutionary adaptations in residues with unknown functions.

CardIAP is a web application that automates the analysis of calcium fluorescence imaging data to identify spatio-temporal patterns and extract quantitative information on calcium dynamics.

ProtMiscuity is a manually-curated database of promiscuous proteins containing 57 proteins from 40 organisms with 88 reactions, providing annotated data linked to other resources.