MicrobiologyNaturePeer-reviewed
A minimal CRISPR polymerase produces decoy cyclic nucleotides to detect phage anti-defense proteins
Ashley E. Sullivan, Ali Nabhani, Daniel S. Izrailevsky…·Benjamin R. Morehouse
The paper identifies a novel antiphage system, Panoptes, that uses a minimal CRISPR polymerase to produce cyclic nucleotides and detects phage anti-defense proteins through effector binding and nucleotide depletion.
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