Spinal Circuit Mechanisms Constrain Therapeutic Windows for ALS Intervention
Beck Strohmer, Kaitlyn Grosh, Roser Montañana-Rosell, Santiago Mora, Jessica Ausborn, Ilary Allodi
The paper develops a spiking neural network model of spinal circuits to predict optimal therapeutic windows for ALS intervention by analyzing the effects of V1 interneuron stabilization.
bioRxiv · Jun 30, 2025 · PreprintNeuroscience