Cancer BiologyCancer DiscoveryPeer-reviewed
Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium
Anagha Inguva Sheth, Krysta L. Engel, Hunter Tolison…·Craig T. Jordan
This study identifies mitochondrial calcium utilization as a metabolic requirement of venetoclax-resistant acute myeloid leukemia stem cells and shows that targeting mitochondrial calcium uptake can eradicate these cells.
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