Briallen Lobb

AnnoView provides a web tool for exploring and comparing gene neighborhoods across microbial genomes, supporting both large databases and user-uploaded datasets.

The paper identifies a novel botulinum neurotoxin-like gene cluster in Bacillus toyonensis, showing it shares structural and functional features with known BoNTs.

The paper identifies two divergent botulinum neurotoxin homologs in Paeniclostridium ghonii and characterizes their structural and functional features.

The paper identifies ancient Clostridium tetani genomes and TeNT variants from archaeological remains, revealing new species and a pathogenic toxin variant.

AnnoTree visualizes and explores functional annotations across 24,000 bacterial genomes, revealing widespread phylogenetic patchiness in gene families.

The paper analyzes ABC transporter gene expression in human airway epithelial cells under cigarette smoke, COPD, and asthma conditions, identifying differentially expressed transporters and validating findings with an in vitro model.