Jennifer A. Aguiar

This paper identifies intronic regulatory elements of ACE2 that respond to immune signaling and oxidative stress, influencing ACE2 expression and viral susceptibility.

The paper analyzes ABC transporter gene expression in human airway epithelial cells under cigarette smoke, COPD, and asthma conditions, identifying differentially expressed transporters and validating findings with an in vitro model.

This study compares the effects of cannabis and tobacco smoke on human airway epithelial cells, showing similar impairments in barrier function and antiviral responses, with no benefit from formoterol/budesonide treatment.