Michael J. Mansfield

NOVOLoci improves genome assembly using Oxford Nanopore reads, achieving high-quality phased assemblies for complex and non-model organisms.

This paper investigates how gene loss and duplication in Fgf subfamilies influenced chordate evolution, particularly in appendicularians, revealing evolutionary patterns and functional shifts.

This study reports the first complete mitogenome assembly of Oikopleura dioica, revealing a high proportion of A and T homopolymers.

The paper shows extreme genome scrambling in cryptic Oikopleura dioica species, revealing high rates of gene order rearrangements and insights into synteny conservation mechanisms.

The paper identifies two divergent botulinum neurotoxin homologs in Paeniclostridium ghonii and characterizes their structural and functional features.

The paper identifies ancient Clostridium tetani genomes and TeNT variants from archaeological remains, revealing new species and a pathogenic toxin variant.

The paper presents a chromosome-scale genome assembly of Oikopleura dioica using Nanopore, Illumina, and Hi-C data, revealing chromosomal structure and genomic features.

The paper identifies new relatives of botulinum neurotoxins in environmental bacteria, revealing their evolutionary origins and divergence from related toxin families.