Author

Casper F. T. van der Ven

ORCID 0000-0001-7947-6105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chahrazad Lachiheb· 2 shared Dimitrios L. WagneriD· 2 shared Emily Ohlendorf· 2 shared Jonas KathiD· 2 shared Julia MacosiD· 2 shared Kathleen AndersiD· 2 shared Maria StecklumiD· 2 shared Maximilian PilgramiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Chahrazad Lachiheb

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 4, 2026

A Non-Viral CRISPR/Cas9 HDR Platform for Stable Engineering of Solid Tumor Models.

Shoaib Afzal, Maximilian Pilgram, Julia Macos…·Michael Launspach

This paper develops a non-viral CRISPR/Cas9 HDR platform for stable transgene knock-in in solid tumor models, achieving up to 60% efficiency in neuroblastoma cells.

DOI 10.64898/2026.06.01.729035

humanCRISPR screen

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BioengineeringNature CommunicationsPeer-reviewedDec 9, 2025

Personalized CRISPR Knock-In Cytokine Gene Therapy to Remodel the Tumor Microenvironment and Enhance CAR T Cell Therapy in Solid Tumors

Michael Launspach, Julia Macos, Shoaib Afzal…·Annette Künkele

This paper develops CancerPAM, a bioinformatics pipeline for identifying CRISPR knock-in sites to remodel the tumor microenvironment, enhancing CAR T cell therapy in solid tumors.

9 citations

humanCRISPR screen

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