ImmunologyCancer ResearchPeer-reviewed
Selective inflammation of the tumor microenvironment and invigorated T cell-mediated tumor control upon induced systemic inactivation of TREX1
Emilija Marinković, Minyi Chen, Nadja Schubert…·Axel Roers
This study shows that systemic TREX1 inhibition enhances anti-tumor immunity by increasing T cell infiltration and activity in tumors while sparing other tissues.
11 citations