Author

Jennifer M. Sahni

Bristol-Myers Squibb (United States)ORCID 0000-0002-2735-1789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Axel RoersiD· 1 shared C. Mark HilliD· 1 shared Christine TuniD· 1 shared Elif Doğan DariD· 1 shared Emilija MarinkovićiD· 1 shared Jack LohreiD· 1 shared Janet Y. LeungiD· 1 shared Michael J. BarnesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Axel RoersORCID

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1 paper

Recent·Most cited

Selective inflammation of the tumor microenvironment and invigorated T cell-mediated tumor control upon induced systemic inactivation of TREX1

Emilija Marinković, Minyi Chen, Nadja Schubert, Elif Doğan Dar, Tanja Poth, Janet Y. Leung, Jack Lohre, Jennifer M. Sahni, Christine Tun, Pavithra Rajeswaran, Tanja Mehlo-Jensen, Olivia A. Perng, C. Mark Hill, Pallavur Sivakumar, Michael J. Barnes, , Axel Roers

This study shows that systemic TREX1 inhibition enhances anti-tumor immunity by increasing T cell infiltration and activity in tumors while sparing other tissues.

Cancer Research · May 12, 2025Peer-reviewedImmunology