N-Glycosylation of MRS2 balances aerobic and anaerobic energy production by reducing rapid mitochondrial Mg2+ influx in conditions of high glucose or impaired respiratory chain function
Min Peng, Neal D. Mathew, Vernon E. Anderson, Marni J. Falk, Eiko Nakamaru‐Ogiso
This study shows that N-glycosylation of MRS2, a mitochondrial Mg2+ transporter, regulates Mg2+ influx and balances energy production under high glucose or impaired respiration.
bioRxiv · Jul 9, 2024 · PreprintBiochemistry