Vernon E. Anderson

This paper shows that DCA improves survival, growth, neuromuscular activity, mitochondrial function, and reduces lactate in C. elegans models of PDHc deficiency.

This study evaluates metabolic and mitochondria-targeted therapies for osteosarcoma using in vitro models, finding that combined treatments like ONC201/ONC206/metformin show enhanced cytotoxicity with minimal toxicity to normal cells.

This study shows that cognate amino acid treatment improves growth, neuromuscular function, and reduces stress in 19 C. elegans models of mt-ARS deficiency.

This study generates ndufs2-/- zebrafish with CI deficiency, showing metabolic and neuromuscular defects treatable by folic acid.

This study shows that N-glycosylation of MRS2, a mitochondrial Mg2+ transporter, regulates Mg2+ influx and balances energy production under high glucose or impaired respiration.