GeneticsThe FASEB JournalPeer-reviewed
A Synthetic, Closed-Looped Gene Circuit for the Autonomous Regulation of RUNX2 Activity during Chondrogenesis
Gurcharan Kaur, Biming Wu, Sanjana Murali…·Rhima M. Coleman
The paper designs a synthetic gene circuit to autonomously regulate RUNX2 activity during chondrogenesis, enhancing matrix synthesis and resisting ECM degradation.