Author

Paul Clinton Spiegel

Western Washington UniversityORCID 0000-0001-7982-5424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Elise F. Tahti· 1 shared James McCartyiD· 1 shared Jeanine F. AmacheriD· 1 shared John M. AntosiD· 1 shared Nathan G AveryiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Elise F. Tahti

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1 paper

Recent·Most cited

BiochemistryThe Journal of Physical Chemistry BPeer-reviewedDec 9, 2025

An interaction between the transmembrane domains of Streptococcus pyogenes sortase A and its endogenous substrate M protein revealed by molecular dynamics simulations

Nathan G Avery, Elise F. Tahti, Paul Clinton Spiegel…·Jeanine F. Amacher

The paper uses molecular dynamics simulations to model the interaction between Streptococcus pyogenes sortase A and its substrate M protein, revealing stereochemical features and potential transmembrane domain interactions that may enhance catalytic efficiency.

1 citation

protein structuremechanistic / dynamical model

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