BiochemistryThe Journal of Physical Chemistry BPeer-reviewed
An interaction between the transmembrane domains of Streptococcus pyogenes sortase A and its endogenous substrate M protein revealed by molecular dynamics simulations
Nathan G Avery, Elise F. Tahti, Paul Clinton Spiegel…·Jeanine F. Amacher
The paper uses molecular dynamics simulations to model the interaction between Streptococcus pyogenes sortase A and its substrate M protein, revealing stereochemical features and potential transmembrane domain interactions that may enhance catalytic efficiency.