BioinformaticsbioRxivPreprint
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
Laurence St. Pierre, Asres Berhan, Eun Kyu Sung…·Zea Borok
The paper identifies TRIP13 as a mediator of AT2 cell dysfunction in IPF through integrated transcriptomic and epigenomic analysis and shows TRIP13 inhibition prevents mesenchymal gene signature acquisition.
DOI 10.1101/2024.04.05.588292