Author

Juan Andres Melendez

University at Albany, State University of New YorkORCID 0000-0001-8021-3097Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sara EvkeiD· 2 shared Thomas J. BegleyiD· 2 shared Andrea LeonardiiD· 1 shared Laura S. Van WinkleiD· 1 shared Lauren EndresiD· 1 shared Lei YiniD· 1 shared Nataliia Kovalchuk· 1 shared Peter C. DedoniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Sara EvkeORCID

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2 papers

Recent·Most cited

Molecular BiologyGenesPeer-reviewedFeb 25, 2022

Epitranscriptomic reprogramming is required to prevent stress and damage from acetaminophen

Sara Evke, Juan Andres Melendez, Qishan Lin, Thomas J. Begley

This study shows that acetaminophen induces epitranscriptomic reprogramming, and Alkbh8 is critical for regulating selenoprotein production and mitigating APAP toxicity.

20 citations

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintAug 7, 2019

Epitranscriptomic regulation of the response to the air pollutant naphthalene in mouse lungs: from the perspectives of specialized translation and tolerance linked to the writer ALKBH8

Andrea Leonardi, Nataliia Kovalchuk, Lei Yin…·Thomas J. Begley

This study investigates the role of ALKBH8 in protecting mouse lungs from naphthalene toxicity, showing increased sensitivity in its deficiency and a protective effect on lung function.

DOI 10.1101/727909

mousebulk RNA-seq

𝕏 PostBluesky